Sleep and Wakefulness Research

This study identifies a neuroimmune circuit linking chronic stress, REM sleep, and behavioral susceptibility through monocyte-driven microglial remodeling and PV neuron activity.

The paper identifies genes involved in sleep homeostasis in Drosophila by analyzing transcriptomic responses across multiple sleep-wake manipulation methods and datasets.

This study identifies MCH neurons in the hypothalamus as a key circuit linking tau pathology to sleep disruption and shows their potential as a therapeutic target.

This study shows that timing of auditory stimulation during sleep affects spindle dynamics and memory consolidation, with post-spindle stimulation improving motor memory but not word recall.

This study examines yawn functions in juvenile Emperor cichlids, finding support for arousal, social contagion, and sex-specific differences in yawn timing and frequency.

This study examines how natural and auditory-evoked slow waves affect cardiovascular function after sleep, finding that synchronized type I slow waves are linked to cardiovascular responses.

This study investigates whether sleep enhances memory generalization using an online sample and finds no evidence supporting a role for sleep in promoting this process.

The paper identifies a hypothalamic-brainstem activity sequence that drives arousal fluctuations and cortical hemodynamics during drowsiness using fMRI.

The paper identifies a 19-45 Hz thalamic oscillation specific to REM sleep and wakefulness, distinguishing conscious states in humans.

This study investigates how nocturnal awakenings influence dream recall, finding that specific awakening characteristics, not just frequency, affect different types of dream recall.

The paper maps whole-brain neural activity during emergence from isoflurane anesthesia in mice and finds selective subcortical activation rather than global cortical reactivation.

This study shows sleep preserves declarative memories regardless of initial strength, while wakefulness selectively impairs weak memories.

The paper identifies genes involved in stress-induced sleep in C. elegans, highlighting the role of glutamate signaling in sleep regulation.

The paper shows respiratory pauses distinguish sleep states in mice and reveal sleep architecture through respiration.

The paper examines how coordination of sleep oscillations during nREM sleep relates to spatial memory performance in rats, finding region-specific coupling patterns between hippocampal and cortical areas.

This study uses EEG/EMG recordings and machine learning to analyze how time-restricted feeding affects sleep microarchitecture in mice on a high-fat diet, finding it reduces sleep fragmentation and enhances specific NREM substates.

This study investigates how sleep loss affects pre-sleep behaviors in mice, finding that sleep deprivation suppresses nest-building and promotes direct sleep onset.

This study examines longitudinal changes in sleep EEG biomarkers of memory consolidation in middle-aged and older adults, finding declines in SO-sigma coupling and sleep spindle measures linked to synaptic integrity and memory decline.

This study shows that ramelteon increases hippocampal ripple occurrence and amplitude during NREM sleep in mice, potentially supporting its cognitive-enhancing effects.

This study shows that targeted memory reactivation during sleep spindles improves recall-based memory retention, with spindle temporal clustering affecting different memory outcomes.

This study identifies shared neurophysiological patterns in pediatric and adult non-rapid eye movement parasomnias using EEG and source-space analysis.

The paper investigates how theta-band brain synchronization during immediate and post-sleep recall sessions in children supports memory recall dynamics and performance.

This study identifies stk32a as a conserved sleep regulator that links neuropeptidergic signaling to sleep homeostasis by suppressing sensory and motor systems in zebrafish and mice.

JACUZI-SD is a method to induce sleep deprivation in larval zebrafish with minimal stress, reducing total sleep time by 41-64% and eliciting rebound sleep.

The paper introduces a stochastic dynamical model to capture bistable dynamics during sleep onset and shows its parameters correlate with subjective sleepiness reports.

This study analyzes dream content using a multimodal dataset to show how individual traits and external events shape dream experiences.

The paper systematically characterizes limb twitching in preterm infants to assess early motor control during sleep.

This study examines the developmental emergence of tonic and phasic REM sleep in rats, showing sequential differentiation of REM substates with age-dependent changes in neural activity and oscillations.

This study inhibits hippocampal activity during specific sleep phases in rats and shows that memory consolidation requires hippocampal engagement during cortical slow oscillation upstates.

This study shows that closed-loop auditory stimulation can restore sleep homeostasis in Alzheimer's and Parkinson's disease models by modulating cortical synchrony and arousal.