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The paper develops and validates a computational tool to predict treatment outcomes in HGSOC cells, showing its potential for preclinical research and personalized medicine.

This study uses generative adversarial networks to perform virtual staining of osteoclast cultures, showing that input image background influences staining predictions and enabling non-invasive analysis.

This paper introduces a yeast mating-based platform for generating ultra-large antibody libraries and demonstrates its ability to discover high-affinity binders.

This paper develops ultrabright NIR-II nanoprobes using molecular and protein engineering for ex vivo bioimaging, showing improved brightness and stability over existing clinical dyes.

This study optimizes velocity receptor (VR) transduction in CAR T cells by evaluating vector modifications and transduction efficiency, finding that VR5IL8 and VR5TNF perform best.

This paper enhances laser lithotripsy efficiency using a PEDOT:PSS nanofluid, achieving significant improvements in stone ablation without increased thermal injury.

This study demonstrates that peptide amphiphile nanostructures enhance cancer imaging and therapy by hitchhiking on endogenous biomolecules to target tumors effectively.

This paper develops tumor-targeting gene drive vectors that eliminate drug resistance in solid tumors through systemic delivery, showing durable tumor burden reduction with minimal toxicity.

The paper introduces miOPM, a reconfigurable LSFM platform that enables high-resolution imaging across multiple spatial scales and refractive indices.

This study develops a combined coating method for dendritic cell membrane-coated nanoparticles, showing improved protein coating and size control, and validates their antigen-specific T cell engagement.

This paper proposes and evaluates C3.5 photosynthesis, a novel strategy to enhance Rubisco efficiency by coupling mitochondrial bioenergetics to chloroplast carbon assimilation in Arabidopsis.

The paper develops bioengineered human tonsil organoids (BTOs) to study immune functions, showing they support antigen-specific responses and immune-stromal interactions comparable to native tissues.

This study evaluates anaerobic co-digestion of sewage sludge and food waste using single- and two-stage reactors with and without carriers, finding that two-stage systems with carriers achieve the highest biogas production and stability.

This study identifies markers distinguishing TIL expansion properties and develops SIN-based strategies to enhance expansion and activation of both low- and high-expanding TILs.

This study develops a data-driven model to estimate joint-space inertia of the lower limb during locomotion, showing improved accuracy compared to rigid body models.

This study identifies sex-based differences in integrin expression and endothelial cell adhesion to bioactive hydrogels, highlighting the need to consider biological sex in biomaterial design.

This study uses liquid TEM to visualize the three-step mineralization process of calcium phosphate on titanium dioxide nanoparticles, revealing dynamic structural changes and electron beam effects.

miniVec is a new plasmid backbone that eliminates antibiotic resistance genes and improves plasmid yield and functionality for clinical applications.

This paper uses protein language models to discover new-to-nature protein domains with structures outside known CATH superfamilies, suggesting natural protein structure-space is incomplete.