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This study evaluates bioengineered microRNA therapies combined with low-dose chemotherapy to treat high-risk neuroblastoma, showing improved efficacy and reduced toxicity.

The paper investigates a dual-strategy approach using a muscle-tropic AAV capsid and muscle-specific promoter to improve gene delivery efficiency and reduce off-target expression in skeletal muscle.

This paper quantifies ORR estimation error in low-photon count data and provides an analytical solution validated with simulations and experiments.

This paper develops a biomaterial-based system that sequentially recruits immune cells and delivers cytokines to treat ischemia-reperfusion acute kidney injury.

This paper develops PT-enhanced kidney organoids with S3-like cells to model physiological responses in CKD, showing improved functionality and scalability.

This paper introduces a phase-noise tolerant OCTA method that improves contrast and enables 3D microvasculature mapping with high SNR correction and coherent averaging.

This paper develops a theory of bone mechanosensing and adaptation based on osteocytes, showing how setpoint adaptation during remodelling affects bone response and may lead to hysteresis.

This study develops a proteomimetic polymer based on angiotensin-(1-7) for topical treatment of corneal injury, showing reduced inflammation, edema, and neovascularization in a mouse model.

The paper develops an L-threonine-inducible biosensor using E. coli's trp promoter for screening high-producing strains and improves ThrB variants for increased L-threonine production.

This paper develops a cell-based therapy that enables sustained, dose-tunable delivery of monoclonal antibodies through a single administration, demonstrating long-term efficacy and safety in preclinical models.

This study shows that a flexible decellularized dermis can be vascularized around a single vein, with fibroblasts enhancing vascularization, and demonstrates improved vascular outcomes compared to subcutaneous implantation.

This paper introduces a microfluidic chip that enables single-cell-constrained impedance sensing in high-density microbial cultures for real-time monitoring in industrial biomanufacturing.

This paper quantifies how spatial degradation and temporal acquisition affect flow biomarkers in a CFD benchmark, showing that spatial degradation increases nRMSE while temporal acquisition impacts PI error and timing.

This paper develops a microfluidic device for high-throughput encapsulation of cells in hydrogel microbeads, achieving high cell viability and microbead stability for microtissue engineering applications.

This study identifies Tween 20 as a surfactant that enhances colorimetric glucose sensing on paper by preserving enzyme activity during drying, improving detection limits and signal stability.

This paper presents a computational framework for embedding wear estimation in musculoskeletal simulations, demonstrating its feasibility in total hip arthroplasty.

BrightEyes-Scope provides a reference implementation for SPAD array-based image scanning microscopy, offering guidelines for system construction and image reconstruction to improve super-resolution imaging.

This study examines how age, sex, and bicuspid aortic valve influence mechanical properties and residual stress in ascending thoracic aortic aneurysms.

This paper develops deep learning models to detect neuromuscular diseases and quantify movement impairment using video-derived biomechanics data from smartphone recordings.

This paper demonstrates that localized delivery of immunotherapeutic agents via hydrogel depots enhances synergistic anti-tumor immunity in mouse tumor models.