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Compression Sequencing improves scRNA-seq sensitivity and reduces cost by logarithmically transforming molecular abundances to enhance rare transcript detection.

This paper introduces spatial-filtering nanoscopy (SFN), a label-free super-resolution Raman imaging technique achieving 40 nm resolution without exogenous labels.

The paper describes a method to measure chlorophyll in moss using a modified microscope with spectral analysis, comparing color imaging and spectral sampling.

This paper describes the scalable production of a de novo SARS-CoV-2 antiviral miniprotein in E. coli, achieving high purity and yield for preclinical and clinical use.

This paper introduces a method using solid ionic matrices with low-temperature evaporation to improve MALDI-MSI sensitivity and resolution for small metabolites, achieving detection of 73 metabolites in mouse brain.

This paper introduces FIMPA, a framework for multi-parametric NIR-II fluorescence perfusion imaging to quantitatively evaluate stroke, validated in mice.

This paper develops a nanoheater-thermometer to measure subcellular temperature and monitor HSF1 responses in living cells, showing that localized heating induces HSF1 foci at lower temperatures than whole-cell heating.

This study examines age- and sex-related differences in inflammatory crosstalk between bone, tendon, and muscle tissues in mice, finding altered cytokine secretion and communication patterns with aging.

This study predicts how muscle fibre type distribution affects gait biomechanics and metabolic cost across different locomotion speeds.

HRV-GUI is a MATLAB tool for HRV analysis across human, rodent, and diabetic gastroparesis data, showing physiologically plausible results and validation across synthetic and clinical datasets.

This study shows that delayed introduction of EDG in an RGD-decorated hydrogel promotes fibroblast-to-myofibroblast transition by increasing myofibroblast markers and ECM proteins.

AutoBlot enables deterministic single-cell western blotting, revealing proteomic diversity in rare cell populations with high occupancy and resolution.

This study uses finite element modeling to analyze how uterine and cervical structural properties affect cervical mechanical loading during pregnancy, identifying key parameters influencing preterm birth risk.

This study uses banana peduncle fibers and mycelium to create sustainable composites for packaging and insulation, finding optimal formulations for strength and thermal properties.

This paper develops a label-free diagnostic platform for HIV detection with smartphone integration, achieving attomolar sensitivity without sample pre-treatment.

This paper develops sequence-defined digital bottlebrush polymers for targeted oligonucleotide delivery, achieving organ-specific therapeutic effects in a mouse model.

This study shows that the viscoelastic properties of an alginate ECM regulate collagen fiber self-assembly through mechanical coupling.

This study shows that adding complex substrates to simplified methanogenic communities can restore diversity but may reduce process stability and methane production.

This study induces skeletal muscle, neuronal, and endothelial cells from bovine embryonic stem cells and demonstrates their self-organization into vascularized tissue structures.

This paper develops a multilayered extracellular matrix scaffold that guides progenitor cell differentiation in vitro and improves osteochondral tissue repair in vivo without exogenous cells or growth factors.