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This paper introduces a low-cost DIY device for high-throughput generation of uniform-sized spheroids, validated with multiple cell lines and drug testing.

This study shows that real-time feedback on error-related potentials during perceptual training enhances error detection ability, outperforming conventional feedback methods.

The paper shows that hydrodynamic dispersion in porous media enhances viral-cellular collisions, improving transduction efficiency by overcoming sedimentation-diffusion limitations.

This study evaluates the longitudinal effects of high-dose irradiation on vertebral bone mechanics, architecture, and composition in rats, finding progressive deterioration in mechanical properties and trabecular structure.

This paper develops IL2-NP nanoparticles that enhance CD8 T-cell expansion and reprogram the tumor microenvironment, showing efficacy in multiple cancer models.

This study evaluates how blood flow affects cochlear temperature during localized hypothermia using experimental and computational methods, finding that vascular heat transport significantly influences cooling effectiveness.

This study develops a biofabrication strategy combining vascular and hypertrophic cartilage microtissues with 3D-printed scaffolds to create scalable, prevascularized grafts for endochondral bone repair.

This paper introduces a minimally invasive hybrid brain-computer interface that improves signal quality and scalability over existing non-invasive and invasive systems.

This paper develops a lipid nanoparticle co-delivering mRNA and a small molecule drug to treat oral cancer by enhancing chemotherapy and reshaping the tumor microenvironment.

This study identifies how liver sinusoidal endothelial cells decode mechanical cues from blood flow during regeneration, showing distinct regenerative programs driven by shear stress and stretch.

This paper introduces a photosoftening hydrogel that dynamically modulates mechanical properties for 3D tissue engineering, showing enhanced cell spreading in human mesenchymal stromal cells.

This study shows that gold coatings on subretinal implants cause retinal inflammation and neuronal loss, while platinum and titanium coatings reduce these effects, enabling better visual resolution implants.

This study develops affibody-conjugated hydrogels to phase the delivery of VEGF, FGF-2, and PDGF, enhancing in vitro angiogenesis by 2.8-fold in vascular network length and 4.1-fold in branching.

This paper validates a mass-based ADM1 model for anaerobic co-digestion of maize silage and cow manure, showing high predictive accuracy with R2 values of 0.81 and 0.85 in calibration and validation tests.

This paper analyzes esophageal compression during ACDF surgery using mechanical models and experiments, showing that blade design changes can reduce tissue stress and mitigate postoperative dysphagia.

The paper identifies a native inhibitor, TrI9, from Trichoderma reesei that suppresses protease activity, improving recombinant protein production by reducing proteolysis without compromising strain fitness.

This paper engineers the bacterial cellulose-forming surface to recruit proteins, creating functionalized biocomposites with improved material properties.

SparseSeg improves cryo-vEM segmentation with sparse annotations by using exemplar-driven propagation and multi-kernel U-Net for accurate, context-aware organelle detection.

This study uses rt3DE-based finite element analysis to assess biomechanics of functional tricuspid regurgitation and evaluate the effects of free wall approximation.

A prediction-guided FGF21 construct with a longer C-terminus gave less protein than the literature design yet concentrated to 1.4 mg/mL versus 0.7 mg/mL (n = 1).