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This paper studies resource-mediated tissue competition using mathematical models and simulations, showing the emergence of travelling wave patterns that depend on population fitness and resource dynamics.

Live E. coli gyrase clusters hold excess GyrB (B:A 2.5:1), show hexanediol-sensitive liquid-like turnover, and docking suggests GyrB bridges heterotetramers.

The paper develops a quantitative theory of enzymatic catalysis in phase-separated systems, showing condensates can act as tunable catalytic switches with optimal activity at biologically relevant sizes.

This study shows the 8S caveolin complex generates positive membrane curvature through a conical shape, with cholesterol affecting curvature via stress relief rather than direct binding.

This study uses molecular dynamics simulations to show how lipid headgroup properties and cholesterol concentration cooperatively regulate domain registration and anti-registration in model membranes.

This paper introduces a method to measure spontaneous curvature in cellular membranes using tether pulling and simulations, revealing baseline negative curvature and its modulation by treatments.

This paper determines the cryo-EM structure of CbrA, revealing its SLC5-STAC domains and how CbrX interacts with the transporter, providing insights into histidine transport and signaling mechanisms.

This study provides NMR resonance assignments and secondary structure analysis of the human 5MP1 C-terminal domain, revealing structural discrepancies between experimental data and AlphaFold predictions.

The paper models metastatic dissemination using a Markovian transport model on a directed network, showing a fast-mixing regime and convergence to a non-equilibrium steady state consistent with clinical observations.

This study uses 4D-STEM to visualize nanoscale dynamics in protein microcrystals, revealing continuous rearrangements and radiolytic damage propagation.

This study investigates the assembly and conformational dynamics of insect odorant receptor complexes using high-speed atomic force microscopy and cryo-EM, revealing non-tetrameric oligomeric states and symmetry-broken configurations.

This paper presents an integrative structural analysis of the bacteriophage Ar-KM, revealing structural polymorphism and the role of ejection proteins in genome ejection.

This study shows how phosphorylation tuning affects Nhp6A's conformational equilibria and DNA binding modes, revealing a conserved mechanism for chromatin regulation.

This study identifies an ER retention motif in hERG1b that enforces a fixed 2:2 stoichiometry in hERG1a/1b channels, with disruption leading to random subunit composition.

This paper introduces a method combining rotational and translational single-particle tracking to analyze nanoscale dynamics, showing it reveals distinct biophysical features of cellular compartments.

The paper introduces cFAR and Relative Signal to diagnose preferred orientation in single-particle cryo-EM, using synthetic and real datasets to validate their effectiveness.

The paper proposes a framework for how infrared photons from sunlight can modulate mitochondrial electron-transfer kinetics, suggesting a new concept called photometabolism.

This study reveals that INO80 reorients on a nucleosome upon ATP hydrolysis, enabling DNA translocation through a unique mechanism distinct from other chromatin remodelers.

This paper introduces a DNA origami nanomechanical amplifier that translates molecular conformational changes into measurable mechanical displacements, enabling single-molecule analysis of binding events without labeling or fluorescence.