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The paper argues that cross-validation overestimates genomic selection's effectiveness in plant breeding, especially when used for accuracy improvement rather than selection intensity.

The paper identifies rs3769823 as a functional variant near CASP8 influencing its expression in a cell-type specific manner and associated with multiple cancers.

This study identifies the roles of PIF1, RAD54, and RDH54/TID1 in Phase 2 meiotic recombination in budding yeast, showing RDH54/TID1 partially compensates for RAD54 while PIF1 acts independently.

This study investigates how genomic inversions affect trait variation and the effectiveness of GWAS methods in detecting associations within inverted regions in Drosophila melanogaster.

This paper introduces a method to deliver synthetic haplotypes containing T2D GWAS variants to hiPSCs to study their functional impact on differentiation.

The paper introduces sedimix, an open-source workflow for analyzing hominin nuclear DNA sequences from sediments, demonstrating high sensitivity and precision through simulations and comparisons to published studies.

The paper uses 3D craniofacial data and genome-wide association analysis to link craniofacial variation to genetic diversity, evolutionary processes, and clinical conditions in modern humans.

This study identifies HvbZIP33 and HvbZIP76 as key regulators of transpiration in drought-stressed barley, showing their role in maintaining water use efficiency.

This study identifies a shared genetic regulator linking metabolism and addiction-related behavior in mice and humans through a common enhancer regulating Eed/Me3 and EED/ME3.

The paper uses single nuclei RNA-sequencing to identify cell-type-specific gene expression dysregulation in the frontal cortex of an Angelman syndrome pig model.

This study evaluates airborne eDNA detection of Bennetts wallabies using active and passive samplers, finding active samplers and coarse filters improve detection, especially at short distances.

This paper describes a novel rat model with an exon 45 deletion in the Dmd gene, showing features of DMD and exon skipping, which may inform personalized therapies.

The paper reports altered hepatic metabolism in Down syndrome using multi-omic analysis of plasma and mouse models, showing increased bile acids and liver dysfunction that can be modulated by diet.

The paper identifies a genetic variant that protects against clonal hematopoiesis by regulating RNA-binding protein MSI2 in hematopoietic stem cells.

The paper identifies genomic features distinguishing neuromuscular disorder genes from other genes using machine learning and statistical analysis.

GrgPhenoSim is a fast phenotype simulator for Genotype Representation Graphs, outperforming existing tools on large-scale datasets.

The paper develops genomic approaches to build elite gene pools from locally-adapted landraces, finding that QGI effectively identifies elite pairs while cis-elite crosses yield better genetic gain.

This paper presents a stochastic model of epigenetic change and proposes three testable predictions about how organisms track environments through epigenetic responses, highlighting gaps in experimental validation.

The paper identifies and validates stable QTL for spike traits under heat stress across 15 environments and develops genomic resources for breeding heat-tolerant wheat.

The paper examines genetic diversity and structure within the Olotillo maize race in Mexico, finding that genetic clusters align with geographic origin rather than race identity, and highlights inbreeding and directional selection across scales.