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The paper presents chromosome-scale genome assemblies for two notothenioid fish species, providing insights into their evolutionary history and adaptation to climate change.

The paper introduces a platform that directly sequences 3'UTRs and guide RNAs in fixed cells alongside protein abundance and morphology, enabling CRISPR screening in lung cancer cells.

The paper presents the first complete and annotated genome of Nereocystis luetkeana, a northeastern Pacific bull kelp, providing insights into its genomic diversity and evolutionary features.

BioFrame provides a web-based tool for reproducible and accessible genomics workflows using containerized microservices.

The paper introduces Agro-STARR-seq, an in planta enhancer screening method, and uses AI to design synthetic enhancers, identifying 14,715 active sequences in Arabidopsis.

The paper introduces scJLIM, a cluster-free method for single-cell colocalization testing, improving power to link GWAS loci with gene expression changes in specific cell types.

The paper maps somatic mutation burden and functional impact across the cancer genome using telomere-to-telomere sequencing, revealing novel mutation hotspots and regulatory rewiring mechanisms.

The paper presents the first complete chloroplast genome of Paeonia suffruticosa 'Cun Song Ying', compares it with related species, and identifies potential DNA barcode regions.

The paper identifies a spatial coordination between mRNA initiation and termination sites, proposing a 'Positional Initiation-Termination Axis' that influences isoform diversity.

The paper introduces Telomere-C, a method to map telomeric 3D interactions, revealing ultra-long-range contacts and repetitive element hubs linked to telomere maintenance.

The paper presents the first chromosome-level genome assembly of the golden jackal using PacBio HiFi sequencing, providing a resource for studying its genetics and ecological impact.

The paper investigates mitonuclear discordance in Tropidurus lizards, finding that ancient mitochondrial introgression and demographic processes explain the observed genetic mismatches.

This study investigates how 3D genome organization changes during breast cancer progression using Hi-C and epigenomic data, revealing structural alterations linked to oncogenic gene activation.

This study shows that transient nuclear softening with TSA treatment enhances cell migration and matrix formation in porcine meniscal cells, with full restoration of transcriptional phenotype and function within 7 days.

The paper presents a high-quality genome assembly of Drosophila melanogaster ovarian somatic cells to study piRNA biology and transposon control.

The paper analyzes the expression and regulatory patterns of CDG-causative genes across tissues to explain phenotypic variability in congenital disorders of glycosylation.

The paper benchmarks somatic mutation detection methods using short-read and long-read sequencing across multiple samples, showing improved accuracy with donor-specific assemblies and highlighting the complementary value of bulk, single-cell, and duplex analyses.

This study reports two multidrug-resistant Phytobacter isolates from human colonization, highlighting their plasmid-borne carbapenemase and antimicrobial resistance profiles.

This study compares human and mouse ovarian biology across age using 3D-imaging, single-cell transcriptomics, and functional studies, identifying species-specific and age-related changes in follicle dynamics and gene expression.

This study uses DNA barcoding with the mat-K gene to reliably identify Ageratum conyzoides Linn leaf samples and confirms its effectiveness for medicinal plant identification.