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The paper identifies human-specific gene expansions linked to brain evolution by analyzing genome sequences and functional models in zebrafish.

Flashzoi improves the Borzoi model by using rotary positional encodings and FlashAttention-2, achieving faster training and inference with reduced memory usage while maintaining accuracy in genomic analysis.

The paper investigates genomic plasticity in Magnaporthe oryzae by analyzing supernumerary mini-chromosomes and their structural variations.

The paper introduces TCAT, a pipeline to annotate T-cell GEPs, identifying 46 reproducible programs across diverse tissues and diseases.

The paper introduces a method to link single-cell imaging and gene expression data through multimodal droplet barcoding, identifying genes correlated with phenotypic features.

This study identifies GRHL2 as a co-regulator of PR in breast cancer cells, showing their interaction and shared regulation of gene enhancers through chromatin looping.

reelGene evaluates gene models using machine learning and evolutionary data, finding 28% of maize gene models are incorrectly annotated or nonfunctional.

The paper presents the first chromosome-level genome assembly of the Siberian flying squirrel, providing insights into its evolutionary relationships and conservation genetics.

This study evaluates the impact of host traits on metagenomic library preparation from dental calculus across 32 mammals, identifying diet-related challenges and success factors.

This study investigates how the absence of Caveolin-1 affects mammary gland metabolism and its impact on fetoplacental cytokine signaling through integrative metabolomics and transcriptomics analyses.

This study optimizes MERFISH protocols to improve RNA imaging performance in cell culture and tissue samples.

The paper benchmarks somatic mutation detection in noncancerous cells using single-cell and single-molecule whole-genome sequencing to assess platform-specific biases and their impact on mutation detection.

This paper evaluates adaptive sampling in Oxford Nanopore long-read sequencing, finding it increases ROI coverage but shows positional effects.

The paper examines the relationship between recent non-LTR retrotransposon activity and cancer prevalence across mammals, finding associations between L1 and SINE activity with neoplasia and malignancy.

The paper presents chromosome-level genome assemblies for two wild cherry species, revealing structural variations and insights into their evolutionary relationships.

This study investigates epigenomic changes in left and right atria of atrial fibrillation patients compared to controls, identifying dysregulated loci and epigenetic mechanisms.

This study sequenced the genome of Bombus haematurus, a range-expanding bumblebee, and found genomic signatures of recent population expansion and selection in developmental and signaling genes.

This study refines the Feulgen protocol to provide accurate and low-cost genome size measurements using ethanol-preserved samples, validated against sequencing data.

This study uses metagenomic analysis to examine microbial diversity in shrimp pond sediments, revealing salinity-driven variations in bacterial communities and their potential impact on shrimp health.

The paper introduces a spatial long-read sequencing method to study developmental splicing and polyadenylation changes in cortical layers and cell types, finding layer-specific and age-related regulatory patterns.