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This paper develops a humanized anti-fibrotic antibody with a collagen-binding peptide to enhance targeting of fibrotic tissues and reduce post-traumatic scarring.

This study quantifies RRV titers in eriophyoid mites using qRT-PCR, revealing active replication in P. fructiphilus and no replication in P. adalius.

This study investigates how RANKL inhibition affects bone formation in a mouse model of fibrous dysplasia, finding that bone formation is restricted to specific surfaces rather than occurring diffusely.

This paper develops a method to quantify immunohistochemistry antigen concentrations and reaction-diffusion parameters, enabling more rigorous interpretation of IHC results.

The paper analyzes the topology of fibroblastic reticular cell networks in lymph nodes to predict breast cancer outcomes, finding that denser networks correlate with better or worse survival depending on disease stage and treatment.

The paper models IL-6 response in severe malaria using an ex vivo co-culture system and clinical data, showing that IL-6 is context-dependent and influenced by metabolic and thermal cues.

This study shows that PAD4-dependent NETosis and MPO contribute to inflammation, fibrosis, and arrhythmias in ACM, with targeting these pathways improving cardiac function.

This study identifies DNA damage-driven senescence and ZBP1-cGAS-STING signaling as conserved mechanisms linking cardiovascular-kidney-metabolic comorbidities to HFpEF.

This study develops an age- and sex-structured model to estimate Chikungunya transmission and optimize control strategies, identifying asymptomatic males aged 15-59 as the core transmission group and highlighting mosquito suppression as the most effective intervention.

This study characterizes a chronic UV-induced photoaging mouse model, showing reduced HA content, altered DNA repair, and increased adipogenesis over eight weeks.

The paper investigates the potential threat of Cassava witches' broom disease fungus to cacao trees in French Guiana through cross-pathogenicity trials and PCR diagnostics.

This paper introduces a rapid H-ORO staining protocol for zebrafish frozen sections that preserves tissue integrity and reduces artifacts compared to traditional methods.

This paper introduces MambaWSI, a state space model for whole slide image classification that extracts multi-scale local and global features, achieving better performance than existing methods.

This study identifies the sPRR/AT1R/Yap/Taz axis in macrophages as a driver of renal fibrosis in UUO by promoting M2 polarization and fibrotic gene expression.

This study uses Drosophila midgut to investigate SARS-CoV-2-induced gastrointestinal pathogenesis, finding disrupted epithelial architecture, altered lipid homeostasis, and partial mitigation by Plitidepsin.

This study identifies MPO as a post-translational inhibitor of CatK, linking acute inflammation to sustained fibrosis through impaired collagen degradation.

This study shows that METTL14-dependent m6A modification prevents myocarditis and dilated cardiomyopathy by restraining IFN signaling and necroptosis in cardiomyocytes.

This study analyzes the causes of death in stranded cetaceans in the Canary Islands from 2013-2018, finding that natural causes accounted for 73.6% of deaths, anthropogenic causes for 12.9%, and 13.4% were undetermined.

Sequenced HBV from wild Amazonian primates in a deforested, densely settled region matched human genotypes A and D, while pristine-forest monkeys were all negative, consistent with human-to-primate spillover.