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This paper shows that targeting CIP4-CaNAβ2 signalosomes improves cardiac function and reduces remodeling after myocardial infarction in mice.

This study evaluates the impact of heat stress on rapeseed grain yield during two phases of grain filling in southern Chile, finding that Lumen is more heat-tolerant than Solar CL.

This study uses a hormetic model to show how temperature thresholds affect survival and fertility resilience in Drosophila melanogaster after cold shock.

This study shows that female reproduction increases mitochondrial oxygen consumption and reduces energy efficiency in Japanese quail, while male reproduction has no effect on mitochondrial function.

This study shows that GPER signaling maintains β cell identity in female mice, and its loss during menopause may contribute to β cell dysfunction and T2D risk.

This study shows that physical activity enhances gut adaptations, hormone sensitivity, and appetite regulation, aiding in body weight maintenance.

This study tests if thermoneutral housing prevents social isolation-induced bone loss in male mice but finds no such effect, suggesting cold stress is not the primary mechanism.

The paper creates a spatio-cellular map of the mouse nodose ganglia using single nucleus RNA sequencing and spatial transcriptomics, revealing subtype-specific gene expression and spatial organization.

This study examines how age and sex hormones affect female neuromuscular function across adulthood, finding accelerated decline around menopause linked to hormonal changes and muscle vulnerability.

This study shows that HDAC3's cardioprotective role in adult hearts is independent of its enzymatic activity, as enzyme-inactive HDAC3 can rescue gene expression and cardiac function.

This study evaluates the metabolic demand of e-bike riding at different intensities and finds that e-bike assistance reduces metabolic demand below the threshold for cardiorespiratory benefits.

This study examines genotype-dependent responses to water deficit in maize, finding increased cell wall digestibility linked to reduced p-coumaric acid and lignification in the rind.

This study shows that enteropancreatic neurons expressing NTSR1 mediate olive oil's effect on glucose tolerance by stimulating insulin release.

This study shows that loss of CnAβ1 enhances brown adipocyte differentiation and metabolic activity through FoxO1 activation, leading to improved insulin sensitivity and reduced body weight on a high-fat diet.

This study develops a computational model of calcium homeostatic feedback to simulate atrial fibrillation progression from healthy to remodeled tissue.

This study examines how aging, endurance training, and denervation affect immune signaling and mitochondrial function in skeletal muscle, finding that training reduces age-related inflammation and mitochondrial dysfunction.

This study shows rapamycin reduces arterial mineral density and improves vascular structure in Mgp-/- mice with medial arterial calcification, though calcification volume remains unchanged.

This study examines bilateral neuromuscular adaptation after unilateral resistance exercise in older adults, finding reduced MVC in both legs but no change in MU potentials in the non-exercised limb.