Pharmacologic Inhibition of Ferroptosis Attenuates Experimental Abdominal Aortic Aneurysm Formation
J. R. Krebs, P. Bellotti, J. A. C. Valisno, G. Su, S. Sharma, D. J. M. Kollareth, J. Hartman, A. Adithan, M. Spinosa, M. Kamat, T. Garrett, G. Cai, A. K. Sharma, G. R. Upchurch
This study shows that inhibiting ferroptosis with liproxstatin-1 reduces AAA formation by decreasing inflammation and aortic remodeling in mice.
bioRxiv · Jun 18, 2024 · PreprintImmunology