Occidiofungin, an actin binding antifungal with in vivo efficacy in a vulvovaginal candidiasis infection
A. Ravichandran, M. Geng, K. G. Hull, D. Romo, S.-E. Lu, A. Albee, C. Nutter, D. Gordon, M. A. Ghannoum, S. W. Lockless, L. Smith
This paper identifies occidiofungin, a novel antifungal compound produced by Burkholderia contaminans, which targets actin and shows efficacy in treating vulvovaginal candidiasis in mice with reduced host toxicity.
bioRxiv · Jul 13, 2018 · PreprintMicrobiology