Author

D. Romo

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Cancer Biology· 2 Cell Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Assay:bulk RNA-seq· 2 Research Focus:cancer & tumor microenvironment· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

K. G. Hull· 3 shared M. Zhu· 3 shared K. Hull· 2 shared A. Albee· 1 shared A. Basseville· 1 shared A. Boari· 1 shared A. Evidente· 1 shared A. Gupta· 1 shared

Activity by Year

2018-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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3 shared papersBiochemistry

K. G. Hull

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Combined HDAC and eIF4A inhibition: A novel epigenetic therapy for pancreatic adenocarcinoma

M. Safari, L. Scotto, A. Basseville, T. Litman, H. Xue, L. Petrukhin, P. Zhou, D. V. Morales, C. Damoci, M. Zhu, K. Hull, K. P. Olive, T. Fojo, D. Romo, S. E. Bates

This paper shows that combining HDAC and eIF4A inhibitors effectively treats pancreatic cancer by inducing epigenetic reprogramming and metabolic stress in preclinical models.

bioRxiv · Jun 30, 2024Cancer Biology

Patterning of phase-separated condensates by Dnd1 controls cell fate

K. J. Westerich, K. Tarbashevich, A. Gupta, M. Zhu, K. Hull, D. Romo, T. Gross-Thebing, E. Raz

The paper investigates how Dnd1 organizes nanos3 RNA within zebrafish germ granules and shows its role in maintaining germ cell totipotency.

bioRxiv · Oct 20, 2022Cell Biology

Roles of the second-shell amino acid R266 in other members of the MLE subgroup of the enolase superfamily

D. P. Truong, S. Fults, C. Davila, J. P. Huddleston, D. Brock, M. Zhu, J.-P. Pellois, K. G. Hull, D. Romo, F. M. Raushel, M. E. Glasner

This study examines how the R266 residue affects NSAR and OSBS activities in multiple NSAR/OSBS subfamily members, showing that its impact varies due to sequence context and epistasis.

bioRxiv · Mar 3, 2022 · PreprintBiochemistry

Necator americanus Ancylostoma secreted protein-2 (Na-ASP-2) selectively binds an ascaroside (ascr#3)

O. El Atab, R. Darwiche, N. J. Truax, R. Schneiter, K. G. Hull, D. Romo, O. A. Asojo

This study investigates whether Na-ASP-2 binds to ascarosides or their fatty acid moieties, finding that ascaroside fatty acids specifically bind to Na-ASP-2's palmitic acid binding cavity.

bioRxiv · Aug 7, 2020Biochemistry

Epithelial-mesenchymal transition sensitizes breast cancer cells to cell death via the fungus-derived sesterterpenoid ophiobolin A

K. N. Reisenauer, Y. Tao, S. Song, S. Patel, A. Ingros, P. Sheesley, M. Masi, A. Boari, J. H. Taube, A. Evidente, A. Kornienko, D. Romo

This study shows that breast cancer cells with EMT features are more sensitive to the cytotoxic effects of ophiobolin A, suggesting its potential as a targeted therapy.

bioRxiv · May 6, 2020Cancer Biology

Occidiofungin, an actin binding antifungal with in vivo efficacy in a vulvovaginal candidiasis infection

A. Ravichandran, M. Geng, K. G. Hull, D. Romo, S.-E. Lu, A. Albee, C. Nutter, D. Gordon, M. A. Ghannoum, S. W. Lockless, L. Smith

This paper identifies occidiofungin, a novel antifungal compound produced by Burkholderia contaminans, which targets actin and shows efficacy in treating vulvovaginal candidiasis in mice with reduced host toxicity.

bioRxiv · Jul 13, 2018 · PreprintMicrobiology