Pharmacology & ToxicologybioRxivPreprint
SARS-CoV-2 inhibition in human airway epithelial cells using a mucoadhesive, amphiphilic chitosan that may serve as an anti-viral nasal spray
K. Pyrc, A. Milewska, E. B. Duran…·I. F. Uchegbu
This paper demonstrates that GCPQ, a mucoadhesive chitosan derivative, reduces SARS-CoV-2 infectivity in cell cultures and shows promising nasal retention in mice, supporting its potential as a nasal spray for COVID-19 prevention.