Mycobacterial infection of precision cut lung slices reveals that the type 1 interferon pathway is locally induced by Mycobacterium bovis but not M. tuberculosis in different cattle breeds
A. Remot, F. Carreras, A. Coupe, E. Doz-Deblauwe, M.-L. Boschiroli, J. A. Browne, Q. Marquant, D. Descamps, F. Archer, A. Aseffa, P. Germon, S. V. Gordon, N. Winter
The paper uses precision-cut lung slices to compare immune responses to Mycobacterium bovis and M. tuberculosis in two cattle breeds, finding that M. bovis induces the type I interferon pathway while M. tuberculosis does not.
bioRxiv · Apr 16, 2021Immunology