N. Winter

IFN-γ primes bone marrow neutrophils to acquire regulatory functions in severe viral respiratory infections

The paper identifies PD-L1+ neutrophils in severe viral respiratory infections, showing they have regulatory functions and are generated in the bone marrow via IFN-γ.

Neutrophil subsets play dual roles in tuberculosis by producing inflammasome dependent-IL-1β or suppressing T-cells via PD-L1

The paper identifies two neutrophil subsets in tuberculosis with opposing roles: one promoting inflammation via IL-1β and another suppressing T-cells via PD-L1.

BIG participates in the Arg/N-degron pathways and the hypoxia response in Arabidopsis thaliana.

This study identifies BIG as a component of N-degron pathways in Arabidopsis, showing it works with PRT6 to regulate hypoxia response and other processes.

MHC-II expressing neutrophils circulate in blood and milk during mastitis and show high microbicidal activity

This study identifies MHC-II expressing neutrophils in blood and milk during mastitis, showing higher microbicidal activity and correlation with T lymphocytes in subclinical cases.

Structural Diversity of Photoswitchable Sphingolipids for Optodynamic Control of Lipid Raft Microdomains

This study develops photoswitchable sphingolipids to control lipid raft microdomains in model membranes using light-induced isomerization.

Caspase-1-driven neutrophil pyroptosis promotes an incomplete NETosis upon Pseudomonas aeruginosa infection

This study shows that Pseudomonas aeruginosa induces Caspase-1-dependent pyroptosis in neutrophils, leading to incomplete NETosis and promoting bacterial spread.

Mycobacterial infection of precision cut lung slices reveals that the type 1 interferon pathway is locally induced by Mycobacterium bovis but not M. tuberculosis in different cattle breeds

The paper uses precision-cut lung slices to compare immune responses to Mycobacterium bovis and M. tuberculosis in two cattle breeds, finding that M. bovis induces the type I interferon pathway while M. tuberculosis does not.

Neutrophils encompass a regulatory subset suppressing T cells in apparently healthy cattle and mice

The paper identifies a regulatory subset of neutrophils in mice and cattle that suppress T cell proliferation through MHC-II expression and contact-dependent mechanisms.

Expression atlas of Selaginella moellendorffii provides insights into the evolution of vasculature, secondary metabolism and roots

The paper presents a gene expression atlas for Selaginella moellendorffii, revealing evolutionary insights into vascular traits, secondary metabolism, and root development.

Experimental infection of cattle with Mycobacterium tuberculosis isolates shows the attenuation of the human tubercle bacillus for cattle

This study infects cattle with M. tuberculosis isolates to show their attenuation compared to M. bovis and explores biomarkers of disease progression using RNA-Seq.