Development of a Novel Air-Liquid Interface Airway Tissue Equivalent Model for In Vitro Respiratory Modeling Studies
T. Leach, U. Gandhi, K. Reeves, K. Stumpf, K. Okuda, F. Marini, S. Walker, J. Chan, L. A. Cox, A. Atala, S. V. Murphy
This study develops a 3D airway tissue equivalent model with native fibroblasts, solubilized ECM, and tunable hydrogel to better mimic human airway biology and assess its impact on epithelial differentiation.
bioRxiv · Sep 21, 2022 · PreprintCell Biology