DLK-dependent biphasic reactivation of herpes simplex virus latency established in the absence of antivirals
S. A. Dochnal, H. Merchant, A. Schinlever, A. Babnis, D. P. Depledge, A. Wilson, A. R. Cliffe
This paper introduces a new HSV-1 reporter virus, Stayput-GFP, to study latency and reactivation in neurons without antivirals, revealing DLK-dependent Phase I reactivation and histone demethylase-dependent Phase II reactivation.
bioRxiv · Feb 25, 2022Microbiology