Quantitative clonal analysis reveals vast heterogeneity among fallopian tube cells for ovarian cancer-initiation and progression
J. Zeng, A. A. Yela, E. Casarez, Y. Jiang, L. Wang, B. E. Kelly, E. Ke, T. M. Jenkins, K. A. Atkins, K. A. Janes, J. K. Slack-Davis, H. Zong
This study uses quantitative clonal tracing in mice to show that only a rare subset of distal fallopian tube cells can initiate and progress serous ovarian cancer.
bioRxiv · Jan 23, 2022 · PreprintCancer Biology