Generation of antigen-specific memory CD4 T cells by heterologous immunization enhances the magnitude of the germinal center response upon influenza infection
L. M. Sircy, A. G. Ramstead, H. Joshi, A. Baessler, I. Mena, A. Garcia-Sastre, M. A. Williams, J. S. Hale
This study shows that heterologous immunization primes antigen-specific memory CD4 T cells, enhancing early germinal center response but not antibody generation in influenza infection.
bioRxiv · Aug 29, 2023Immunology