Critical role for Slam/SAP signaling in the thymic developmental programming of IL-17- and IFN-γ-producing γδ T cells
O. Dienz, V. L. DeVault, S. C. Musial, S. K. Mistri, L. Mei, A. Baraev, J. A. Dragon, D. Krementsov, A. Veillette, J. E. Boyson
This study shows that SLAM/SAP signaling is critical for thymic development of IL-17 and IFN-γ-producing γδ T cells, with subset-specific dependencies.
bioRxiv · Oct 11, 2019Immunology