Spatial control of nucleoporin assembly by Fragile X-related proteins
A. Agote-Aran, S. S. Schmucker, K. J. Jerabkova, I. Jmel Boyer, A. Berto, L. Pacini, P. Ronchi, C. Kleiss, L. Guerard, Y. Schwab, H. Moine, J.-L. Mandel, S. Jacquemont, C. Bagni, I. Sumara
This paper shows that FXR proteins and dynein help localize nucleoporins to the nuclear envelope and prevent their cytoplasmic aggregation, which affects nuclear morphology and G1 cell cycle progression.
bioRxiv · Sep 12, 2019 · PreprintCell Biology