Author

I. Sumara

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 4 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Organism:human· 5 Research Focus:cell signaling & trafficking· 4 Assay:proteomics· 3 Research Focus:chromatin & epigenetic regulation· 2 Research Focus:development & morphogenesis· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

C. Kleiss· 4 shared A. Agote-Aran· 3 shared Y. LIAO· 3 shared E. Pangou· 2 shared L. Guerber· 2 shared L. Ran· 2 shared Z. ZHANG· 2 shared A. Berto· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 34 mutual co-author links

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4 shared papersCell Biology

C. Kleiss

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

UBAP2L drives scaffold assembly of nuclear pore complexes at the intact nuclear envelope

Y. LIAO, L. Andronov, X. Liu, J. Lin, L. Guerber, L. Lu, A. Agote-Aran, E. Pangou, L. Ran, C. Kleiss, M. Qu, S. Schmucker, L. Cirillo, Z. ZHANG, D. Riveline, , I. Sumara

This study identifies UBAP2L's role in assembling functional nuclear pore complexes at the nuclear envelope by facilitating Y-complex formation and interactions with key nucleoporins.

bioRxiv · Aug 21, 2023 · PreprintCell Biology

KCNN4 links PIEZO-dependent mechanotransduction to NLRP3 inflammasome activation

L. Ran, T. Ye, E. Erbs, S. Ehl, N. Spassky, I. Sumara, Z. Zhang, R. Ricci

The paper identifies KCNN4 as a mediator linking PIEZO mechanotransduction to NLRP3 inflammasome activation, showing its role in CAPS-related auto-inflammation.

bioRxiv · Mar 8, 2023Immunology

UBAP2L-dependent coupling of PLK1 localization and stability during mitosis

L. Guerber, A. Vuidel, Y. Liao, C. Kleiss, E. Grandgirard, I. Sumara, E. Pangou

This study identifies UBAP2L as a regulator of PLK1 localization and stability during mitosis, showing its role in maintaining genome fidelity through ubiquitin-mediated turnover.

bioRxiv · Oct 24, 2022Cell Biology

Deubiquitylase UCHL3 drives error correction at kinetochores and chromosome segregation independent of spindle assembly checkpoint

K. Jerabkova, Y. Liao, C. Kleiss, S. Fournane, M. Durik, A. Agote-Aran, L. Brino, R. Sedlacek, I. Sumara

bioRxiv · Mar 31, 2020 · PreprintCell Biology

Spatial control of nucleoporin assembly by Fragile X-related proteins

A. Agote-Aran, S. S. Schmucker, K. J. Jerabkova, I. Jmel Boyer, A. Berto, L. Pacini, P. Ronchi, C. Kleiss, L. Guerard, Y. Schwab, H. Moine, J.-L. Mandel, S. Jacquemont, C. Bagni, I. Sumara

This paper shows that FXR proteins and dynein help localize nucleoporins to the nuclear envelope and prevent their cytoplasmic aggregation, which affects nuclear morphology and G1 cell cycle progression.

bioRxiv · Sep 12, 2019 · PreprintCell Biology