Author

A. Best

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1 Assay:proteomics· 1 Approach:statistical model· 1 Organism:zebrafish· 1

Frequent Co-Authors

A. M. Thompson· 1 shared F. Fenaroli· 1 shared G. Griffiths· 1 shared G. Schafer· 1 shared J. Ojong· 1 shared J. Wohlmann· 1 shared K. Johann· 1 shared K. Koynov· 1 shared

Activity by Year

2022-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperBioengineering

A. M. Thompson

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2 papers

Recent·Most cited

A sterility-mortality tolerance trade-off leads to within-population variation in host tolerance.

P. Singh, A. Best

The paper investigates a trade-off between sterility and mortality tolerance in hosts, showing it can lead to dimorphic strain coexistence and altered disease prevalence patterns.

bioRxiv · Nov 5, 2022Evolutionary Biology

{Pi}-{Pi} Interactions Stabilize PeptoMicelle-Based Formulations of Pretomanid Derivatives Leading to Promising Therapy Against Tuberculosis in Zebrafish and Mouse Models

N.-J. K. Dal, G. Schafer, A. M. Thompson, S. Schmitt, N. Redinger, N. Alonso-Rodriguez, K. Johann, J. Ojong, J. Wohlmann, A. Best, K. Koynov, R. Zentel, U. E. Shaible, G. Griffiths, M. Barz, F. Fenaroli

This paper develops PeptoMicelle-based formulations of pretomanid derivatives using π-π interactions, showing improved efficacy against tuberculosis in zebrafish and mouse models.

bioRxiv · Mar 10, 2022Bioengineering