Vγ usage distinguishes pro- and anti-tumor intestinal γδ T cell subsets
B. S. Reis, P. W. Darcy, I. Z. Khan, O. Eleso, C. Zhu, M. Schernthanner, A. Lockhart, A. Reed, J. Bortolatto, T. Castro, A. Bilate, S. Grivennikov, D. Mucida
The paper identifies Vγ1+ and Vγ7+ γδ T cells as anti-tumor and RORγt+ subsets, including Vγ4+ and Vγ6+, as pro-tumor in colorectal cancer.
bioRxiv · Nov 13, 2021 · PreprintImmunology