Metabolically activated macrophages in mammary adipose tissue link obesity to triple-negative breast cancer
P. Tiwari, A. Blank, C. Cui, K. Schoenfelt, G. Zhou, Y. Xu, A. Shah, S. Khan, M. R. Rosner, L. Becker
This study shows that obesity-induced metabolically activated macrophages in mammary adipose tissue promote triple-negative breast cancer stemness and tumorigenesis through GP130 signaling.
bioRxiv · Jul 17, 2018Cancer Biology