Author

A. Bosma

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

R. Bernards· 2 shared A. Berninger· 1 shared A. Marreiros· 1 shared A. Mulero-Sanchez· 1 shared A.-T. Maia· 1 shared B. P. de Almeida· 1 shared B. Sainz· 1 shared B. Thijssen· 1 shared

Activity by Year

2021-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersCancer Biology

R. Bernards

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Combined SHP2 and ERK inhibition for the treatment of KRAS-driven Pancreatic Ductal Adenocarcinoma

K. J. Ciecielski, A. Mulero-Sanchez, A. Berninger, L. R. Canas, A. Bosma, K. Gorgulu, N. Wu, K. N. Diakopoulos, E. Kaya-Aksoy, D. A. Ruess, D. Kabacaoglu, F. Schmidt, L. Heinemann, Y. Fan, B. Thijssen, , S. Mainardi

This paper investigates the combination of SHP2 and ERK inhibition as a treatment for KRAS-driven pancreatic ductal adenocarcinoma, showing synergistic anticancer effects and tumor regression in mouse models.

bioRxiv · Dec 14, 2021 · PreprintCancer Biology

Allelic expression imbalance of PIK3CA mutations is frequent in breast cancer and prognostically significant

L. W. Correia, J. M. Xavier, R. Magno, B. P. de Almeida, F. Esteves, I. Duarte, M. Eldridge, C. Sun, A. Bosma, L. Mittempergher, A. Marreiros, R. Bernards, C. Caldas, S.-F. Chin, A.-T. Maia

The paper identifies frequent allelic expression imbalance of PIK3CA mutations in breast cancer and links it to poor prognosis.

bioRxiv · Mar 5, 2021Cancer Biology