Author

A. Bruning-Richardson

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:clustering· 1 Assay:DNA methylation· 1

Frequent Co-Authors

L. F. Stead· 3 shared A. Brodbelt· 2 shared A. Chakrabarty· 2 shared A. Droop· 2 shared A. Ismail· 2 shared G. Tanner· 2 shared N. Rippaus· 2 shared R. Barrow· 2 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 43 mutual co-author links

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3 shared papersCancer Biology

L. F. Stead

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Author profile →

3 papers

Recent·Most cited

IDHwt glioblastomas can be stratified by their transcriptional response to standard treatment, with implications for targeted therapy

G. Tanner, R. Barrow, M. Finetti, S. Ajaib, N. Ahmed, S. Pollock, N. Rippaus, A. F. Bruns, K. Syed, J. Poulter, E. A. Wilson, C. A. Johnson, F. S. Varn, A. Bruning-Richardson, C. Hogg, , L. F. Stead

This study identifies two IDHwt glioblastoma subtypes based on transcriptional response to treatment, with distinct resistance mechanisms and potential therapeutic implications.

bioRxiv · Feb 3, 2023Cancer Biology

SpheroidAnalyseR - an online platform for analysing data from 3D spheroids or organoids grown in 96-well plates

R. Barrow, J. N. Wilkinson, Y. He, M. Callaghan, A. Bruning-Richardson, M. Dunning, L. F. Stead

SpheroidAnalyseR is an R Shiny app that enables fast, automated analysis of 3D spheroid or organoid growth data from 96-well plates, improving efficiency and reproducibility.

bioRxiv · Feb 18, 2022Cell Biology

JARID2 facilitates transcriptional reprogramming in glioblastoma in response to standard treatment

N. Rippaus, A. F-Bruns, G. Tanner, C. Taylor, A. Droop, A. Bruning-Richardson, M. A. Care, J. Wilkinson, M. D. Jenkinson, A. Brodbelt, A. Chakrabarty, A. Ismail, S. C. Short, L. F. Stead

The paper identifies JARID2-mediated transcriptional reprogramming in glioblastoma post-treatment, showing dysregulated genes with JARID2 binding sites are universally altered in recurrent tumors.

bioRxiv · Jun 17, 2019 · PreprintCancer Biology