Author

S. Pollock

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Organism:human· 2 Approach:deep learning· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:statistical model· 1

Frequent Co-Authors

A. Chakrabarty· 2 shared A. Gusnanto· 2 shared A. Ismail· 2 shared F. S. Varn· 2 shared L. F. Stead· 2 shared M. Finetti· 2 shared A. A. Brockman· 1 shared A. Brodbelt· 1 shared

Activity by Year

2023-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 42 mutual co-author links

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2 shared papersCancer Biology

A. Chakrabarty

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2 papers

Recent·Most cited

GBMdeconvoluteR accurately infers proportions of neoplastic and immune cell populations from bulk glioblastoma transcriptomics data

S. A. Ajaib, D. Lodha, S. Pollock, G. Hemmings, M. Finetti, A. Gusnanto, A. Chakrabarty, A. Ismail, E. Wilson, F. S. Varn, B. Hunter, A. Filby, A. A. Brockman, D. McDonald, R. Verhaak, , L. F. Stead

This paper develops GBMdeconvoluteR, a tool to accurately infer neoplastic and immune cell proportions in bulk glioblastoma RNAseq data, validated against imaging mass cytometry.

Neuro-Oncology · Jul 6, 2023Peer-reviewedCancer Biology

IDHwt glioblastomas can be stratified by their transcriptional response to standard treatment, with implications for targeted therapy

G. Tanner, R. Barrow, M. Finetti, S. Ajaib, N. Ahmed, S. Pollock, N. Rippaus, A. F. Bruns, K. Syed, J. Poulter, E. A. Wilson, C. A. Johnson, F. S. Varn, A. Bruning-Richardson, C. Hogg, , L. F. Stead

This study identifies two IDHwt glioblastoma subtypes based on transcriptional response to treatment, with distinct resistance mechanisms and potential therapeutic implications.

bioRxiv · Feb 3, 2023Cancer Biology