Author

A. Charbit

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 5

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:host-pathogen & immune response· 4 Organism:human· 3 Assay:metabolomics· 3 Assay:proteomics· 3 Organism:bacteria (other)· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

A. Jamet· 5 shared M. Coureuil· 5 shared E. RAMOND· 4 shared F. Tros· 4 shared D. Euphrasie· 3 shared J. Ziveri· 3 shared C. Chhuon· 2 shared H. Rytter· 2 shared

Activity by Year

2018-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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5 shared papersMicrobiology

A. Jamet

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5 papers

Recent·Most cited

The Pentose Phosphate Pathway constitutes a major metabolic hub in pathogenic Francisella

H. Rytter, A. Jamet, J. Ziveri, E. RAMOND, M. Coureuil, P. Lagouge-Roussey, D. Euphrasie, F. Tros, N. Goudin, C. Chhuon, I. Nemazanyy, F. E. de Moraes, C. Abate, I. C. Guerrera, a. charbit

This study investigates the role of the pentose phosphate pathway in Francisella novicida's intracellular survival and metabolism, showing its critical connections to other metabolic pathways.

bioRxiv · Jan 15, 2021Microbiology

ROS-dependent innate immune mechanisms control Staphylococcus aureus MRSA virulence in the Drosophila larval model

E. Ramond, A. Jamet, X. Ding, C. Bouvier, L. Lallemant, X. He, L. Arbibe, M. Coureuil, A. Charbit

This study uses a Drosophila larval model to show that ROS-dependent innate immune mechanisms control S. aureus MRSA virulence by modulating H2O2 production and antimicrobial peptide responses.

bioRxiv · Oct 2, 2020 · PreprintMicrobiology

A post-translational modification of the sheath 1 modulates Francisella type VI secretion system assembly and function

J. ZIVERI, C. CCHUON, A. JAMET, G. PRIGENT, H. RYTTER, F. TROS, M. BAREL, m. COUREUIL, C. LAYS, t. HENRY, N. KEEP, C. I. GUERRERA, A. CHARBIT

This study identifies a phosphorylation site on IglB that modulates Francisella T6SS assembly and function, showing that phosphorylation is critical for sheath stability and phagosomal escape.

bioRxiv · Feb 22, 2019 · PreprintMicrobiology

Transketolase of Staphylococcus aureus is involved in the control of master regulators of stress response during infection

X. Tan, E. Ramond, a. jamet, B. Decaux-Tramoni, M. Dupuis, d. euphrasie, F. Tros, I. Nemazanyy, J. Ziveri, X. Nassif, A. Charbit, M. Coureuil

This study shows that transketolase in S. aureus affects stress response regulators, impacting bacterial proliferation during infection.

bioRxiv · Feb 15, 2019Microbiology

Chronic Staphylococcus aureus lung infection correlates with proteogenomic and metabolic adaptations leading to an increased intracellular persistence

X. TAN, M. Coureuil, E. Ramond, D. Euphrasie, M. Dupuis, F. Tros, J. Meyer, I. Nemanzny, C. Chhuon, I. C. Guerrera, A. Ferroni, I. Sermet-Gaudelus, X. Nassif, A. Charbit, A. Jamet

This study shows that S. aureus isolates from CF patients have increased intracellular persistence and metabolic adaptations, suggesting an intracellular niche contributes to chronic lung infection.

bioRxiv · Oct 16, 2018Microbiology