Author

A. Chilkoti

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:deep learning· 2 Approach:statistical model· 2 Organism:bacteria (other)· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:metabolism & bioenergetics· 1 Research Focus:protein design· 1

Frequent Co-Authors

R. V. Pappu· 2 shared X. Zeng· 2 shared A. S. Holehouse· 1 shared C. Liu· 1 shared H. Hsu-Kim· 1 shared J. Mohammed· 1 shared K. Kim· 1 shared L. You· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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2 shared papersBiophysics

R. V. Pappu

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3 papers

Recent·Most cited

Global control of cellular physiology by biomolecular condensates through modulation of electrochemical equilibria

Y. Dai, Z. Zhou, K. Kim, N. Rivera, J. Mohammed, H. Hsu-Kim, A. Chilkoti, L. You

This study shows that biomolecular condensates modulate electrochemical gradients in cells, affecting gene expression, membrane potential, and bacterial survival under antibiotic stress.

bioRxiv · Oct 19, 2023 · PreprintCell Biology

Design of intrinsically disordered proteins that undergo phase transitions with lower critical solution temperatures

X. Zeng, C. Liu, M. J. Fossat, P. Ren, A. Chilkoti, R. V. Pappu

This paper designs intrinsically disordered proteins with LCST phase behavior using Monte Carlo simulations and genetic algorithms.

bioRxiv · Nov 13, 2020Biophysics

Connecting coil-to-globule transitions to full phase diagrams for intrinsically disordered proteins

X. Zeng, A. S. Holehouse, A. Chilkoti, T. Mittag, R. V. Pappu

The paper introduces a computational approach to predict sequence-specific phase diagrams for intrinsically disordered proteins by combining simulations with Gaussian cluster theory.

bioRxiv · May 13, 2020Biophysics