Author

A. D. Gossert

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 3 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:protein folding & dynamics· 2 Assay:protein structure· 2 Assay:proteomics· 2 Organism:bacteria (other)· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

A. C. Wolter· 1 shared A. Leitner· 1 shared A. Lingel· 1 shared A. Löbbert· 1 shared B. Shrestha· 1 shared C. Bergsdorf· 1 shared C.-J. Tsai· 1 shared F. H.- T. Allain· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 10 mutual co-author links

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1 shared paperBiophysics

A. C. Wolter

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Author profile →

4 papers

Recent·Most cited

Human Cells for Human Proteins: Isotope Labeling in Mammalian Cells for Functional NMR Studies of Disease-Relevant Proteins

P. Rössler, M. Ruckstuhl, A. Löbbert, T. Stühlinger, L. R. Franchini, C.-J. Tsai, R. Lichtenecker, B. Shrestha, S. H. Rüdisser, R. Konrat, G. F. X. Schertler, A. D. Gossert

The paper develops cost-effective isotope labeling protocols in HEK293 cells for NMR studies of difficult-to-produce human proteins, enabling detailed structural and functional analysis.

bioRxiv · Apr 9, 2024Biophysics

Intrinsically disordered regions in the transcription factor MYC:MAX modulate DNA binding via intramolecular interactions

S. Schuetz, C. Bergsdorf, S. Haenni-Holzinger, A. Lingel, M. Renatus, A. D. Gossert, W. Jahnke

This study identifies intramolecular interactions between intrinsically disordered regions and the DNA binding domain of MYC:MAX, showing they compete with DNA binding and slow complex formation.

bioRxiv · Jun 21, 2023Biophysics

A hybrid structure determination approach to investigate the druggability of the nucleocapsid protein of SARS-CoV-2

G. Padroni, M. Bikaki, M. Novakovic, A. C. Wolter, S. H. Ruedisser, A. D. Gossert, A. Leitner, F. H.- T. Allain

The paper develops a hybrid method combining NMR and mass spectrometry to study RNA binding and druggability of SARS-CoV-2 N-protein, identifying potential drug candidates.

bioRxiv · Sep 15, 2022Biophysics

The Molecular Basis of FimT-mediated DNA Uptake during Bacterial Natural Transformation

S. A. G. Braus, F. L. Short, S. Holz, M. J. M. Stedman, A. D. Gossert, M. K. Hospenthal

This study identifies FimT as a key minor pilin involved in DNA uptake during natural transformation in Legionella pneumophila, showing its direct DNA binding and conserved function across gamma-Proteobacteria.

bioRxiv · Aug 16, 2021Microbiology