B. Shrestha

Human Cells for Human Proteins: Isotope Labeling in Mammalian Cells for Functional NMR Studies of Disease-Relevant Proteins

The paper develops cost-effective isotope labeling protocols in HEK293 cells for NMR studies of difficult-to-produce human proteins, enabling detailed structural and functional analysis.

Prevalence of Class 1 integron in disease-causing carbapenem-resistant Escherichia coli in a tertiary hospital in Kathmandu, Nepal

This study finds high prevalence of Class 1 integrons in carbapenem-resistant E. coli in Nepal, often co-occurring with carbapenemase genes like blaNDM-1.

The Impact of Anesthesia on Ultrasonic Glymphatic Perturbation Protocol: Alertness, and Glymphatic Influx

This study evaluates how isoflurane-induced anesthesia affects ultrasonically enhanced glymphatic transport in rats, finding that lighter anesthesia improves transport efficiency.

Kif9 is an active kinesin motor required for ciliary beating and proximodistal patterning of motile axonemes

This study shows Kif9 is essential for ciliary beating and proper localization of axonemal structures in Xenopus, with both indirect and direct roles in motility.

Hexavalent Sperm-Binding IgG Antibody Released from Self-Dissolving Vaginal Film Enables Potent, On-Demand Non-Hormonal Female Contraception

This paper develops a non-hormonal contraceptive method using a hexavalent sperm-binding antibody delivered via a dissolving vaginal film, showing potent sperm inhibition in sheep.