Cell BiologybioRxiv
Lysosome-related organelles contain an expansion compartment that mediates delivery of zinc transporters to promote homeostasis
A. D. Mendoza, N. Dietrich, C.-H. Tan…·K. Kornfeld
The paper identifies ZIPT-2.3 as a zinc transporter in C. elegans that mediates zinc release during deficiency, revealing a structural expansion compartment in lysosome-related organelles that facilitates homeostasis.
DOI 10.1073/pnas.2307143121