PhysiologybioRxiv
Impact of circadian time of dosing on cardiomyocyte-autonomous effects of glucocorticoids
M. Wintzinger, M. Panta, K. Miz…·M. Quattrocelli
This study shows that circadian timing of glucocorticoid dosing affects heart metabolism and function through cardiomyocyte-autonomous mechanisms, with light-phase dosing improving NAD+ and ATP levels.
DOI 10.1016/j.molmet.2022.101528