Author

A. Da Poian

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Biophysics· 1

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Approach:mechanistic / dynamical model· 1 Research Focus:protein folding & dynamics· 1 Organism:virus· 1

Frequent Co-Authors

A. Pinheiro· 1 shared F. C. L. Almeida· 1 shared I. P. Caruso· 1 shared K. Sanches· 1 shared

Activity by Year

2020-2020 · peak 1/yr

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4 top collaborators · 6 mutual co-author links

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1 shared paperBiophysics

A. Pinheiro

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1 paper

Recent·Most cited

BiophysicsbioRxivPreprintAug 24, 2020

Dynamics of the N-terminal domain of SARS-CoV-2 nucleocapsid protein drives dsRNA melting in a counterintuitive tweezer-like mechanism

I. P. Caruso, K. Sanches, A. Da Poian…·F. C. L. Almeida

This paper uses molecular dynamics simulations to show that the N-terminal domain of SARS-CoV-2 N protein destabilizes dsRNA through a tweezer-like motion, revealing a 1:1 stoichiometry and potential mechanisms for RNA melting.

DOI 10.1101/2020.08.24.264465

virusmechanistic / dynamical model

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