Author

A. de Graff

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Assay:bulk RNA-seq· 1 Organism:C. elegans· 1 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Organism:human· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

C. Weistuch· 1 shared D. E. Mosedale· 1 shared D. Grainger· 1 shared G. Balazsi· 1 shared K. A. Dill· 1 shared T. Matsuzaki· 1 shared T. Sharp· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 9 mutual co-author links

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1 shared paperBiophysics

C. Weistuch

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2 papers

Recent·Most cited

The remarkable similarity in the serum proteome between type 2 diabetics and controls

D. E. Mosedale, T. Sharp, A. de Graff, D. Grainger

This study finds the serum proteome is remarkably similar between type 2 diabetics and controls, with major differences being glycations of abundant proteins and associations between BMI and a ternary complex.

bioRxiv · Mar 19, 2024 · PreprintPathology

Transcriptional drift in aging cells: A global de-controller

T. Matsuzaki, C. Weistuch, A. de Graff, K. A. Dill, G. Balazsi

The paper identifies transcriptional drift in aging C. elegans worms, showing upregulated sensory proteins and downregulated growth/metabolism genes, and proposes a mechanistic model involving ligand binding.

bioRxiv · Nov 21, 2023 · PreprintBiophysics