Cancer BiologybioRxiv
Signalling involving MET and FAK supports cell division independent of the activity of the cell cycle-regulating CDK4/6 kinases
C. Zhang, S. R. Stockwell, M. Elbanna…·S. Mittnacht
This study shows that MET/FAK signaling can activate CDK2 independently of CDK4/6, leading to cell division, and suggests targeting MET/FAK could enhance CDK4/6 inhibitor therapies.
DOI 10.1038/s41388-019-0850-2