Activin E is a TGFβ ligand that signals specifically through activin receptor-like kinase 7.
K. A. Vestal, C. Kattamuri, M. Koyiloth, L. Ongaro, J. A. Howard, A. Deaton, S. Ticau, A. Dubey, D. J. Bernard, T. B. Thompson
This study identifies Activin E as a TGFβ ligand that signals through ALK7, using canonical activin receptors and SMAD2/3 pathways, similar to Activin C.
bioRxiv · Sep 25, 2023Biochemistry