T. B. Thompson

This study identifies Activin E as a TGFβ ligand that signals through ALK7, using canonical activin receptors and SMAD2/3 pathways, similar to Activin C.

This study identifies GDF3 as an obesity-induced regulator that modulates TGFβ superfamily signaling by inhibiting BMP and activating activin-like SMAD 2/3 pathways in adipose tissue.

The paper develops and compares three methods to estimate arrival times in network dynamics, applied to toxic protein propagation in neurodegenerative diseases.

The paper develops personalized tau-atrophy models using clinical data to estimate brain atrophy rates linked to tau pathology in Alzheimer's disease.

This study shows that deleting Grem2 in mice reduces fertility and disrupts estrous cycles, suggesting a role for Grem2 in regulating the HPO axis and female reproductive health.

The paper shows that the non-signaling complex formed by Activin A and ACVR1 reduces disease severity in FOP by tempering heterotopic ossification.

This study determines the structure of human pro-myostatin and identifies features responsible for its latent state, offering insights into myostatin activation and potential inhibitor design.