Structural insights into the recognition of mono- and di-acetylated histones by the ATAD2B bromodomain
J. T. Lloyd, K. McLaughlin, M. Y. Lubula, J. C. Gay, A. Dest, C. Gao, M. Phillips, M. Tonelli, G. Cornilescu, M. R. Marunde, C. M. Evans, S. P. Boyson, S. Carlson, M.-C. Keogh, J. L. Markley, , K. C. Glass
This study investigates the ligand specificity of the ATAD2B bromodomain, showing it binds mono- and di-acetylated histones and identifies structural features critical for this recognition.
bioRxiv · May 12, 2020 · PreprintBiochemistry