JUNB O-GlcNAcylation-mediated promoter accessibility of metabolic genes modulates distinct epithelial lineage in pulmonary fibrosis
M. J. Thomas, M.-T. Bammert, M. Ansari, L. Haag, Z. Ahmad, V. Schroeder, J. Birch, D. Santacruz, W. Rust, C. Viollet, B. Strobel, A. Dick, F. Gantner, H. Schleuter, F. Ramirez, , H. Q. Le
The paper identifies O-GlcNAcylation of JUNB as a regulator of promoter accessibility in metabolic genes, driving aberrant epithelial lineage in IPF.
bioRxiv · May 27, 2024Cell Biology