Cell BiologybioRxiv
A polycomb-independent role of EZH2 in TGFβ1-damaged epithelium triggers a fibrotic cascade with mesenchymal cells
H. Q. Le, M. A. Hill, I. Kollak…·J. P. Garnett
The paper shows that EZH2, independent of Polycomb, drives fibrosis in TGFβ1-damaged epithelium by forming a new transcriptional complex with POL2 and nuclear actin.
DOI 10.15252/embr.202152785