Strong SARS-CoV-2 N-specific CD8+ T immunity induced by engineered extracellular vesicles associates with protection from lethal infection in mice.
F. Ferrantelli, C. Chiozzini, F. Manfredi, P. Leone, M. Spada, A. DiVirgilio, A. Giovannelli, M. Sanchez, A. Cara, Z. Michelini, M. Federico
This paper shows engineered extracellular vesicles induce strong N-specific CD8+ T cell immunity in mice, which protects against lethal SARS-CoV-2 infection.
bioRxiv · Jan 10, 2022Microbiology