High-throughput small molecule screen identifies inhibitors of microsporidia invasion and proliferation in C. elegans.
B. M. Murareanu, N. V. Antao, W. Zhao, A. Dubuffet, H. El Alaoui, J. Knox, D. C. Ekiert, G. Bhabha, P. Roy, A. W. Reinke
This study screens FDA-approved compounds and natural products to identify inhibitors of microsporidia infection in C. elegans, finding five compounds that block spore firing and one that slows infection progression.
bioRxiv · Sep 6, 2021Microbiology