Author

A. Dynka

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Assay:CRISPR screen· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1

Frequent Co-Authors

A. Witkiewicz· 1 shared C. Frangou· 1 shared E. Knudsen· 1 shared E. V. Abel· 1 shared H. Rosenheck· 1 shared J. Wang· 1 shared P. Dey· 1 shared V. Kumarasamy· 1 shared

Activity by Year

2023-2023 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 36 mutual co-author links

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1 shared paperCancer Biology

A. Witkiewicz

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1 paper

Recent·Most cited

Pharmacologically targeting KRASG12D in PDAC models:tumor cell intrinsic and extrinsic impact

V. Kumarasamy, C. Frangou, J. Wang, Y. Wan, A. Dynka, H. Rosenheck, P. Dey, E. V. Abel, E. Knudsen, A. Witkiewicz

This study evaluates KRASG12D inhibition in PDAC models, showing variable efficacy in 2D cultures but enhanced response in 3D cultures and xenografts, with immunological modulation contributing to tumor regression.

bioRxiv · Mar 18, 2023Cancer Biology