Cell BiologybioRxiv
Differential translation of mRNA isoforms underlies oncogenic activation of cell cycle kinase Aurora A
R. Cacioppo, H. B. Akman, T. Tuncer…·C. Lindon
The paper identifies that differential translation of AURKA mRNA isoforms, regulated by miRNA and alternative polyadenylation, contributes to oncogenic activation of Aurora A in breast cancer.
DOI 10.7554/elife.87253