Author

A. E. Loneker

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Physiology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:experimental assay· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:development & morphogenesis· 1 Approach:statistical model· 1

Frequent Co-Authors

R. G. Wells· 3 shared N. D. Theise· 2 shared P. A. Janmey· 2 shared A. Kant· 1 shared C. Fede· 1 shared C. S. Friday· 1 shared C. Stecco· 1 shared E. E. Furth· 1 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 28 mutual co-author links

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3 shared papersPhysiology

R. G. Wells

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Glisson's capsule structure and function is altered in cirrhotic patients irrespective of etiology

J. Llewellyn, C. Fede, A. E. Loneker, C. S. Friday, M. W. Hast, N. D. Theise, E. E. Furth, M. Guido, C. Stecco, R. G. Wells

This study examines changes in Glisson's capsule in liver disease, finding increased thickness and cellularity in cirrhosis regardless of cause, altered matrix composition, and reduced mechanical stiffness.

bioRxiv · Aug 28, 2022 · PreprintPhysiology

Lipid droplets are intracellular mechanical stressors that promote hepatocyte dedifferentiation

A. E. Loneker, F. Alisafaei, A. Kant, P. A. Janmey, V. B. Shenoy, R. G. Wells

This study shows lipid droplets act as intracellular mechanical stressors that cause nuclear deformation and hepatocyte dedifferentiation, similar to tissue stiffening effects.

bioRxiv · Aug 27, 2022 · PreprintCell Biology

Lipid droplets disrupt mechanosensing in human hepatocytes

L. Chin, N. D. Theise, A. E. Loneker, P. A. Janmey, R. G. Wells

This study shows that lipid droplets in hepatocytes disrupt mechanosensing by altering YAP nuclear localization and affecting cell spreading and focal adhesions.

bioRxiv · Mar 31, 2020Physiology