P. A. Janmey

This study shows lipid droplets act as intracellular mechanical stressors that cause nuclear deformation and hepatocyte dedifferentiation, similar to tissue stiffening effects.

The paper examines how fat accumulation in livers with simple steatosis affects liver stiffness, finding that fat softens the liver locally rather than uniformly.

This study identifies versican as a collagen-binding protein that regulates collagen matrix organization and mechanics through its G3 domain.

This paper shows that glycosaminoglycans (GAGs) reduce long-range mechanical communication between cells in collagen networks by preventing collagen fiber alignment.

This paper develops fibrous hydrogel assemblies that contract when encapsulated with mesenchymal stromal cells, enabling programmed shape changes for biofabrication and tissue engineering.

The paper identifies extracellular vimentin as a potential target for preventing SARS-CoV-2 infection by showing it facilitates viral entry through interaction with the spike protein and ACE2.

This study shows that lipid droplets in hepatocytes disrupt mechanosensing by altering YAP nuclear localization and affecting cell spreading and focal adhesions.

This study investigates the role of KIF20A, a kinesin motor protein, in bladder cancer cell mechanics and motility, showing that its inhibition alters intracellular and cortical stiffness.